Single-Step Amphoteric Surface Modification Through Plasma Polymerization: Antifouling Coating for Titanium Substrate

Abstract

In order to improve bacterial antifouling property, titanium (Ti) surfaces were functionalized through the plasma polymerization (PP) technique with diethyl allyl phosphate (DAP) as amphoteric precursor. Antifouling properties of the surfaces were evaluated in vitro by Escherichia coli (ATCC (R) 25922 (TM)) and Staphylococcus aureus (ATCC (R) 25923 (TM)) strain, and results showed that 75.00% and 81.25% bacterial reduction achieved on functionalized surfaces, respectively. In vitro cell culture studies were carried out with BJ normal human skin fibroblast (ATCC (R) CRL-2522 (TM)) cell line. These findings revealed that amphoteric plasma polymer prepared from DAP offers promising solution for preventing Biofilm formation on Ti.