Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/7696
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dc.contributor.authorYavuz, Mustafa Selman-
dc.contributor.authorBüyükserin, Fatih-
dc.contributor.authorZengin, Zuleyha-
dc.contributor.authorÇamlı, Şevket Tolga-
dc.date.accessioned2021-09-11T15:58:57Z-
dc.date.available2021-09-11T15:58:57Z-
dc.date.issued2011en_US
dc.identifier.issn0887-624X-
dc.identifier.issn1099-0518-
dc.identifier.urihttps://doi.org/10.1002/pola.24927-
dc.identifier.urihttps://hdl.handle.net/20.500.11851/7696-
dc.description.abstractThermoresponsive polymeric colloids attract great attention in several biotechnological applications owing to their ability to manipulate drug release characteristics in a controlled manner. Majority of these applications utilized N-isopropylacrylamide (NIPAM)-based particles for controlled drug release. Despite its advantages, such as easy chemical modification and well-documented literature, a potentially important bottleneck for NIPAM in biological applications is its tendency for nonspecific protein adsorption. Herein, we report a simple way to prepare novel thermoresponsive colloids composed of oligo(ethylene glycol) side chains via precipitation polymerization technique. In addition to displaying highly reversible thermal response, these particles also have considerably low nonspecific protein adsorption when compared with NIPAM counterparts. These crosslinked poly(ethylene glycol) ethyl ether methacrylate particles were characterized using dynamic light scattering and transmission electron microscopy. The effects of co-monomer, crosslinker and initiator on particle characteristics were investigated. Finally, particle toxicity studies were carried out using 3T3 fibroblast cell lines in MTT cytotoxicity assay. (C) 2011 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 49: 4800-4808, 2011en_US
dc.description.sponsorshipEuropean CommunityEuropean Commission [248819]en_US
dc.description.sponsorshipThis work was partially supported by Marie Curie International Reintegration Grant within the 7th European Community Framework Program, Project No: 248819.en_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal of Polymer Science Part A-Polymer Chemistryen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectpoly(ethylene glycol) ethyl ether methacrylateen_US
dc.subjectthermoresponsiveen_US
dc.subjectprecipitation polymerizationen_US
dc.subjectantifoulingen_US
dc.subjectbovine serum albumin adsorptionen_US
dc.titleThermoresponsive Oligo(ethylene Glycol) Methacrylate Colloids With Antifouling Surface Propertiesen_US
dc.typeArticleen_US
dc.departmentFaculties, Faculty of Engineering, Department of Biomedical Engineeringen_US
dc.departmentFakülteler, Mühendislik Fakültesi, Biyomedikal Mühendisliği Bölümütr_TR
dc.identifier.volume49en_US
dc.identifier.issue22en_US
dc.identifier.startpage4800en_US
dc.identifier.endpage4808en_US
dc.authorid0000-0002-6436-6373-
dc.authorid0000-0001-6365-3808-
dc.identifier.wosWOS:000296255900011en_US
dc.identifier.scopus2-s2.0-80054040226en_US
dc.institutionauthorBüyükserin, Fatih-
dc.identifier.doi10.1002/pola.24927-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.scopusqualityQ1-
item.openairetypeArticle-
item.languageiso639-1en-
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
crisitem.author.dept02.2. Department of Biomedical Engineering-
Appears in Collections:Biyomedikal Mühendisliği Bölümü / Department of Biomedical Engineering
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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