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https://hdl.handle.net/20.500.11851/6883
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Vural, Metin | - |
dc.contributor.author | Coşkun, Bilgen | - |
dc.contributor.author | Kılıç, Mert | - |
dc.contributor.author | Durmaz, Selahattin | - |
dc.contributor.author | Gümüş, Terman | - |
dc.contributor.author | Cengiz, Duygu | - |
dc.contributor.author | Rozanes, Izzet | - |
dc.date.accessioned | 2021-09-11T15:44:04Z | - |
dc.date.available | 2021-09-11T15:44:04Z | - |
dc.date.issued | 2021 | en_US |
dc.identifier.issn | 0720-048X | - |
dc.identifier.issn | 1872-7727 | - |
dc.identifier.uri | https://doi.org/10.1016/j.ejrad.2021.109785 | - |
dc.identifier.uri | https://hdl.handle.net/20.500.11851/6883 | - |
dc.description.abstract | Purpose: To determine the diagnostic yield of magnetic resonance imaging (MRI) guided in-bore biopsy in pa-tients with high likelihood multiparametric MRI (mpMRI) findings, regarding overall and clinically significant prostate cancer (csPCa) detection rates and concordance of biopsy and radical prostatectomy (RP) Gleason scores (GS). Methods: This retrospective study consisted of 277 Prostate Imaging Reporting and Data System (PI-RADS) assessment category 4 and 5 targets in 246 patients (mean age, 65.7 years; median prostate specific antigen value, 7.75 ng/mL) who had undergone in-bore biopsy at our institution between 2012 and 2020. Eighty-one patients who underwent RP were eligible for the concordance analysis of biopsy and RP specimen GS. Results: Overall PCa detection rates were 80.5 % per patient (198/246) and 78 % per target (216/277) and 83.5 % and 67.4 % in primary (biopsy naive) and secondary (at least one negative prior biopsy) settings. csPCa was found in 63 % overall, 66 % of patients (132/200) in the primary, and 50 % of patients (23/46) in the secondary biopsy settings (p < 0.001). The prostate cancer detection rate was 68 % and 92 % in PI-RADS 4 and 5, respectively (p < 0.001). In the radical prostatectomy subcohort, 27.2 % of patients were upgraded, 8.6 % of patients were downgraded from needle biopsy. Significant complications occurred in 1.2 % of patients. Conclusions: MRI-guided in-bore prostate biopsy has a high detection rate of csPCa in primary and secondary biopsy cohorts. Biopsy results were satisfactory in terms of the number of positive cores, cancer percentage in positive cores, and concordance of GS in needle biopsy and RP specimen. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Elsevier Ireland Ltd | en_US |
dc.relation.ispartof | European Journal of Radiology | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Prostate cancer | en_US |
dc.subject | Magnetic resonance imaging | en_US |
dc.subject | In-bore biopsy | en_US |
dc.subject | Multiparametric MRI | en_US |
dc.subject | PI-RADS | en_US |
dc.title | In-Bore Mri-Guided Prostate Biopsy in a Patient Group With Pi-Rads 4 and 5 Targets: a Single Center Experience | en_US |
dc.type | Article | en_US |
dc.department | Faculties, School of Medicine, Department of Internal Medical Sciences | en_US |
dc.department | Fakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü | tr_TR |
dc.identifier.volume | 141 | en_US |
dc.authorid | 0000-0003-1707-3890 | - |
dc.authorid | 0000-0003-1268-2654 | - |
dc.authorid | 0000-0002-9249-7792 | - |
dc.authorid | 0000-0003-3436-1587 | - |
dc.identifier.wos | WOS:000674500400004 | en_US |
dc.identifier.scopus | 2-s2.0-85107304071 | en_US |
dc.institutionauthor | Onay, Aslıhan | - |
dc.identifier.pmid | 34091134 | en_US |
dc.identifier.doi | 10.1016/j.ejrad.2021.109785 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.scopusquality | Q1 | - |
item.openairetype | Article | - |
item.languageiso639-1 | en | - |
item.grantfulltext | none | - |
item.fulltext | No Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
Appears in Collections: | Dahili Tıp Bilimleri Bölümü / Department of Internal Medical Sciences PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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