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https://hdl.handle.net/20.500.11851/6539
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yıldırım, İsa | - |
dc.contributor.author | Ansari, Rashid | - |
dc.contributor.author | Yetik, İmam Şamil | - |
dc.contributor.author | Shahidi, Mahnaz | - |
dc.date.accessioned | 2021-09-11T15:37:15Z | - |
dc.date.available | 2021-09-11T15:37:15Z | - |
dc.date.issued | 2013 | en_US |
dc.identifier.issn | 0090-6964 | - |
dc.identifier.issn | 1573-9686 | - |
dc.identifier.uri | https://doi.org/10.1007/s10439-013-0831-5 | - |
dc.identifier.uri | https://hdl.handle.net/20.500.11851/6539 | - |
dc.description.abstract | Phosphorescence lifetime imaging is commonly used to generate oxygen tension maps of retinal blood vessels by classical least squares (LS) estimation method. A spatial regularization method was later proposed and provided improved results. However, both methods obtain oxygen tension values from the estimates of intermediate variables, and do not yield an optimum estimate of oxygen tension values, due to their nonlinear dependence on the ratio of intermediate variables. In this paper, we provide an improved solution by devising a regularized direct least squares (RDLS) method that exploits available knowledge in studies that provide models of oxygen tension in retinal arteries and veins, unlike the earlier regularized LS approach where knowledge about intermediate variables is limited. The performance of the proposed RDLS method is evaluated by investigating and comparing the bias, variance, oxygen tension maps, 1-D profiles of arterial oxygen tension, and mean absolute error with those of earlier methods, and its superior performance both quantitatively and qualitatively is demonstrated. | en_US |
dc.description.sponsorship | NATIONAL EYE INSTITUTEUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USANIH National Eye Institute (NEI) [R01EY017918, P30EY001792] Funding Source: NIH RePORTER; NEI NIH HHSUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USANIH National Eye Institute (NEI) [R01 EY017918, P30 EY001792] Funding Source: Medline | en_US |
dc.language.iso | en | en_US |
dc.publisher | Springer | en_US |
dc.relation.ispartof | Annals of Biomedical Engineering | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Phosphorescence lifetime imaging | en_US |
dc.subject | Retinal vasculatures | en_US |
dc.subject | Oxygen tension estimation | en_US |
dc.subject | Spatial regularization | en_US |
dc.title | Direct Regularized Estimation of Retinal Vascular Oxygen Tension Based on an Experimental Model | en_US |
dc.type | Article | en_US |
dc.department | Faculties, Faculty of Engineering, Department of Electrical and Electronics Engineering | en_US |
dc.department | Fakülteler, Mühendislik Fakültesi, Elektrik ve Elektronik Mühendisliği Bölümü | tr_TR |
dc.identifier.volume | 41 | en_US |
dc.identifier.issue | 11 | en_US |
dc.identifier.startpage | 2285 | en_US |
dc.identifier.endpage | 2295 | en_US |
dc.identifier.wos | WOS:000325772900004 | en_US |
dc.identifier.scopus | 2-s2.0-84896709909 | en_US |
dc.institutionauthor | Yetik, Imam Şamil | - |
dc.identifier.pmid | 23732915 | en_US |
dc.identifier.doi | 10.1007/s10439-013-0831-5 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.scopusquality | Q1 | - |
item.openairetype | Article | - |
item.languageiso639-1 | en | - |
item.grantfulltext | none | - |
item.fulltext | No Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | 02.5. Department of Electrical and Electronics Engineering | - |
Appears in Collections: | Elektrik ve Elektronik Mühendisliği Bölümü / Department of Electrical & Electronics Engineering PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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