Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/3787
Full metadata record
DC FieldValueLanguage
dc.contributor.authorDemir, Mustafa-
dc.contributor.authorKalyoncu, Şenol-
dc.contributor.authorİnce, Onur-
dc.contributor.authorÖzkan, Bülent-
dc.contributor.authorKelekci, Sefa-
dc.contributor.authorSağlam, Gülcan-
dc.contributor.authorSütçü, Recep-
dc.contributor.authorYılmaz, Bülent-
dc.date.accessioned2020-09-18T06:37:38Z-
dc.date.available2020-09-18T06:37:38Z-
dc.date.issued2019
dc.identifier.citationDemir, M., Kalyoncu, S., Ince, O., Ozkan, B., Kelekci, S., Saglam, G., ... & Yilmaz, B. (2019). Endometrial Flushing Tumor Necrosis Factor Alpha and Interleukin 2 Levels in Women with Polycystic Ovary Syndrome, Leiomyoma and Endometrioma: Comparison with Healthy Controls. Geburtshilfe und Frauenheilkunde, 79(05), 517-523.en_US
dc.identifier.issn0016-5751
dc.identifier.urihttps://hdl.handle.net/20.500.11851/3787-
dc.identifier.urihttps://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-0829-3873-
dc.description.abstractIntroduction An important open question in the literature is whether endometrial receptivity marker levels are different in infertility related diseases than healthy women. The aim of the study is to compare the levels of interleukin two (IL-2) and tumor necrosis factor alpha (TNF-?) during the implantation window in the endometrial flushing fluid of polycystic ovary syndrome (PCOS), endometrioma, leiomyoma patients with healthy controls. Material and Methods In this case control study, after obtaining endometrial flushing fluids at mid-luteal phase of ovulatory women with PCOS (n = 20), endometrioma (n = 19), leiomyoma (n = 20) and healthy controls (n = 20), IL-2 and TNF-? levels were measured using ELISA kits in BioTek ELISA devices. Results Mean TNF-? levels (ng/mL) were similar for the PCOS (305.6, p = 0.220) and the leiomyoma group (246.3, p = 0.502) compared to healthy patients (261.1). However, the levels were higher in the endometrioma group (338.2, p = 0,004) than the control group (261.1) in a statistically significant way. Mean IL-2 levels (ng/mL) were significantly lower in the PCOS (290.9, p = 0.0005), the leiomyoma (282.9, p = 0.0002) and the endometrioma patients (229.5, p = 0.0009) than the control group (416.0). Conclusion Relative to the control group, endometrial flushing fluid TNF-? levels were significantly higher in endometrioma patients and IL-2 levels were significantly lower in PCOS, leiomyoma and endometrioma patients. In benign gynecological diseases, endometrial markers related to infertility seem to show differences in endometrial flushing fluid. Future studies might identify the reference values for these markers, and endometrial markers can be used to diagnose gynecologic disorders causing infertility.en_US
dc.language.isoenen_US
dc.publisherGeorg Thieme Verlagen_US
dc.relation.ispartofGeburtshilfe und Frauenheilkundeen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectendometrial receptivityen_US
dc.subjectinterleukin 2en_US
dc.subjecttumor necrosis factor alphaen_US
dc.subjectpolycystic ovary syndromeen_US
dc.subjectleiomyomaen_US
dc.subjectendometriomaen_US
dc.titleEndometrial Flushing Tumor Necrosis Factor Alpha and Interleukin 2 Levels in Women With Polycystic Ovary Syndrome, Leiomyoma and Endometrioma: Comparison With Healthy Controlsen_US
dc.typeArticleen_US
dc.departmentFaculties, School of Medicine, Department of Surgical Sciencesen_US
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümütr_TR
dc.identifier.volume79
dc.identifier.issue5
dc.identifier.startpage517
dc.identifier.endpage523
dc.authorid0000-0001-6201-8888-
dc.identifier.wosWOS:000474785900015en_US
dc.identifier.scopus2-s2.0-85065998140en_US
dc.institutionauthorKalyoncu, Şenol-
dc.identifier.pmid31148852en_US
dc.identifier.doi10.1055/a-0829-3873-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.relation.otherIzmir Katip Celebi University [2013-T1-TSBP-11]
dc.identifier.scopusqualityQ2-
item.openairetypeArticle-
item.languageiso639-1en-
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
Appears in Collections:Cerrahi Tıp Bilimleri Bölümü / Department of Surgical Sciences
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
Show simple item record



CORE Recommender

SCOPUSTM   
Citations

1
checked on Dec 21, 2024

WEB OF SCIENCETM
Citations

6
checked on Dec 21, 2024

Page view(s)

58
checked on Dec 23, 2024

Google ScholarTM

Check




Altmetric


Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.