Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/11039
Title: Self-Aligning Nanojunctions for Integrated Single-Molecule Circuits
Authors: Liu, Bo
Demir, Busra
Gultakti, Caglanaz Akin
Marrs, Jonathan
Gong, Yichen
Li, Ruihao
Hihath, Joshua
Keywords: Single-Molecule Electronics
Molecular Devices
Biosensors
Carbon Nanotubes
Nanoelectronics
Nanojunction
Self-Alignment
Publisher: Amer Chemical Soc
Abstract: Robust, high-yield integration of nanoscale components such as graphene nanoribbons, nanoparticles, or single-molecules with conventional electronic circuits has proven to be challenging. This difficulty arises because the contacts to these nanoscale devices must be precisely fabricated with angstrom-level resolution to make reliable connections, and at manufacturing scales this cannot be achieved with even the highest-resolution lithographic tools. Here we introduce an approach that circumvents this issue by precisely creating nanometer-scale gaps between metallic carbon electrodes by using a self-aligning, solution-phase process, which allows facile integration with conventional electronic systems with yields approaching 50%. The electrode separation is controlled by covalently binding metallic single-walled carbon nanotube (mCNT) electrodes to individual DNA duplexes to create mCNT-DNA-mCNT nanojunctions, where the gap is precisely matched to the DNA length. These junctions are then integrated with top-down lithographic techniques to create single-molecule circuits that have electronic properties dominated by the DNA in the junction, have reproducible conductance values with low dispersion, and are stable and robust enough to be utilized as active, high-specificity electronic biosensors for dynamic single-molecule detection of specific oligonucleotides, such as those related to the SARS-CoV-2 genome. This scalable approach for high-yield integration of nanometer-scale devices will enable opportunities for manufacturing of hybrid electronic systems for a wide range of applications.
Description: Liu, Bo/0000-0003-4627-4456; Oren, Ersin Emre/0000-0001-5902-083X; Demir, Busra/0000-0002-3911-2291; Akin Gultakti, Caglanaz/0000-0002-0227-1002; Hihath, Joshua/0000-0002-2949-9293; Marrs, Jonathan/0000-0001-6434-2980
URI: https://doi.org/10.1021/acsnano.3c10844
ISSN: 1936-0851
1936-086X
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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