Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/10852
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dc.contributor.authorÖren,B.-
dc.contributor.authorKızıltoprak,H.-
dc.contributor.authorDüzayak,S.-
dc.contributor.authorOzkoyuncu Kocabaş,D.-
dc.date.accessioned2023-12-23T06:06:31Z-
dc.date.available2023-12-23T06:06:31Z-
dc.date.issued2024-
dc.identifier.issn0816-4622-
dc.identifier.urihttps://doi.org/10.1080/08164622.2023.2251958-
dc.identifier.urihttps://hdl.handle.net/20.500.11851/10852-
dc.description.abstractClinical relevance: Vitiligo is a skin disease characterised by depigmentation and loss of melanocytes. Melanocyte loss may not be limited to the skin in vitiligo, and various abnormalities may occur in the choroid, which is dense in melanocytes. Background: To evaluate structural changes in the choroid by measuring choroidal thickness and vascularity index using optical coherence tomography in patients with vitiligo and comparing them to healthy subjects. Methods: This study included 168 participants: 84 with vitiligo (30 females, 54 males) and 84 controls (36 females, 48 males). Choroidal thickness and vascularity index were measured using the enhanced depth imaging mode in spectral-domain optical coherence tomography. The choroidal thickness was measured at the following five points; subfoveal (SF), 500 μm (NCT1) and 1000 μm (NCT2) nasal to the fovea; and 500 μm (TCT1) and 1000 μm (TCT2) temporal to the fovea. The choroidal vascularity index was calculated using the ImageJ software. Results: SF (p < 0.001), NCT1 (p < 0.001), NCT2 (p = 0.021), TCT1 (p = 0.001), and TCT2 (p < 0.006) choroidal thicknesses were significantly smaller in the vitiligo group than in the control group. Total choroidal (p < 0.001) and stromal (p < 0.001) areas were significantly smaller in the vitiligo group than in the control group. Choroidal vascularity indices were significantly higher in the vitiligo group than in the control group (p < 0.001). However, luminal areas did not differ significantly between groups (p = 0.935). Conclusion: Patients with vitiligo should be regularly monitored for choroidal alterations and, if necessary, referred to an ophthalmologist. © 2023 Optometry Australia.en_US
dc.language.isoenen_US
dc.publisherTaylor and Francis Ltd.en_US
dc.relation.ispartofClinical and Experimental Optometryen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChoroidal thicknessen_US
dc.subjectchoroidal vascularity indexen_US
dc.subjectoptical coherence tomographyen_US
dc.subjectvitiligoen_US
dc.titleChoroidal Vascularity Index and Choroidal Thickness Assessment in Vitiligoen_US
dc.typeArticleen_US
dc.departmentTOBB ETÜen_US
dc.identifier.volume107en_US
dc.identifier.issue5en_US
dc.identifier.startpage558en_US
dc.identifier.endpage562en_US
dc.identifier.wosWOS:001108215200001en_US
dc.identifier.scopus2-s2.0-85177564344en_US
dc.identifier.pmid37993171en_US
dc.identifier.pmidPubMed:37993171-
dc.identifier.doi10.1080/08164622.2023.2251958-
dc.authorscopusid55941363500-
dc.authorscopusid57195289777-
dc.authorscopusid57196213500-
dc.authorscopusid57773526400-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.wosqualityQ3-
item.openairetypeArticle-
item.languageiso639-1en-
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
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