Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.11851/10651
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Özkan, Burak | - |
dc.contributor.author | Savran, Süleyman | - |
dc.contributor.author | Akıncı, Kadri | - |
dc.contributor.author | Albayati, Abbas | - |
dc.contributor.author | İncel Uysal, Pınar | - |
dc.contributor.author | Uysal, Çağrı Ahmet | - |
dc.date.accessioned | 2023-10-24T06:58:59Z | - |
dc.date.available | 2023-10-24T06:58:59Z | - |
dc.date.issued | 2023 | - |
dc.identifier.issn | 1300-0144 | - |
dc.identifier.issn | 1303-6165 | - |
dc.identifier.uri | https://doi.org/10.55730/1300-0144.5638 | - |
dc.identifier.uri | https://hdl.handle.net/20.500.11851/10651 | - |
dc.description.abstract | Background/aim: Hydrochlorothiazide (HCTZ) possesses well-described photosensitizing properties, and a causal association with nonmelanoma skin cancer (NMSC) was recently shown. However, previous studies have not shown whether HCTZ use is associated with the risk of recurrence of basal cell carcinoma (BCC) or squamous cell carcinoma (SCC). This study aims to investigate the association between HCTZ use and recurrence in patients with NMSC.Materials and methods: We identified cases with NMSC from our hospital archives during the period between 2013 and 2019. Patients were divided into groups according to the pathological diagnosis, HCTZ use, and recurrence. Multivariable analysis was performed to determine factors associated with recurrence in BCC and SCC.Results: Recurrences of BCC were significantly higher in HCTZ users with ORs of 4.839221 (95% confidence interval [CI], 1.22-19.12). In HCTZ users, NMSC cases were associated with increased age (p < 0.001 for both BCC and SCC). BCC recurrences were statistically significant with age, longer follow-up, and positive margins after excision in HCTZ users (p = 0.048, 0.020, and, 0.003, respectively). SCC recurrences were not significantly associated with HCTZ use. Conclusion: HCTZ use is significantly associated with BCC recurrences. Especially in the elderly population, cases with a positive margin should be followed closely. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Tubitak Scientific & Technological Research Council Turkey | en_US |
dc.relation.ispartof | Turkish Journal of Medical Sciences | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Cancer | en_US |
dc.subject | hydrochlorothiazide | en_US |
dc.subject | recurrence | en_US |
dc.subject | skin | en_US |
dc.subject | Basal-Cell Carcinoma | en_US |
dc.subject | Risk-Factors | en_US |
dc.subject | Metastasis | en_US |
dc.subject | Population | en_US |
dc.title | The Effect of Hydrochlorothiazide on the Recurrence of Nonmelanoma Skin Cancer: a 7-Year Retrospective Study Comprising 300 Patients | en_US |
dc.type | Article | en_US |
dc.department | TOBB ETÜ | en_US |
dc.identifier.volume | 53 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.startpage | 752 | en_US |
dc.identifier.endpage | 760 | en_US |
dc.identifier.wos | WOS:001022334700015 | en_US |
dc.identifier.scopus | 2-s2.0-85163624085 | en_US |
dc.institutionauthor | … | - |
dc.identifier.pmid | 37476909 | en_US |
dc.identifier.doi | 10.55730/1300-0144.5638 | - |
dc.authorscopusid | 57194264417 | - |
dc.authorscopusid | 57850708200 | - |
dc.authorscopusid | 57218773138 | - |
dc.authorscopusid | 57194474692 | - |
dc.authorscopusid | 56786442900 | - |
dc.authorscopusid | 57222441725 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.scopusquality | Q3 | - |
dc.identifier.trdizinid | 1191047 | en_US |
item.openairetype | Article | - |
item.languageiso639-1 | en | - |
item.grantfulltext | none | - |
item.fulltext | No Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | 03.14. Department of Internal Medicine | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection TR Dizin İndeksli Yayınlar / TR Dizin Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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