Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/10651
Full metadata record
DC FieldValueLanguage
dc.contributor.authorÖzkan, Burak-
dc.contributor.authorSavran, Süleyman-
dc.contributor.authorAkıncı, Kadri-
dc.contributor.authorAlbayati, Abbas-
dc.contributor.authorİncel Uysal, Pınar-
dc.contributor.authorUysal, Çağrı Ahmet-
dc.date.accessioned2023-10-24T06:58:59Z-
dc.date.available2023-10-24T06:58:59Z-
dc.date.issued2023-
dc.identifier.issn1300-0144-
dc.identifier.issn1303-6165-
dc.identifier.urihttps://doi.org/10.55730/1300-0144.5638-
dc.identifier.urihttps://hdl.handle.net/20.500.11851/10651-
dc.description.abstractBackground/aim: Hydrochlorothiazide (HCTZ) possesses well-described photosensitizing properties, and a causal association with nonmelanoma skin cancer (NMSC) was recently shown. However, previous studies have not shown whether HCTZ use is associated with the risk of recurrence of basal cell carcinoma (BCC) or squamous cell carcinoma (SCC). This study aims to investigate the association between HCTZ use and recurrence in patients with NMSC.Materials and methods: We identified cases with NMSC from our hospital archives during the period between 2013 and 2019. Patients were divided into groups according to the pathological diagnosis, HCTZ use, and recurrence. Multivariable analysis was performed to determine factors associated with recurrence in BCC and SCC.Results: Recurrences of BCC were significantly higher in HCTZ users with ORs of 4.839221 (95% confidence interval [CI], 1.22-19.12). In HCTZ users, NMSC cases were associated with increased age (p < 0.001 for both BCC and SCC). BCC recurrences were statistically significant with age, longer follow-up, and positive margins after excision in HCTZ users (p = 0.048, 0.020, and, 0.003, respectively). SCC recurrences were not significantly associated with HCTZ use. Conclusion: HCTZ use is significantly associated with BCC recurrences. Especially in the elderly population, cases with a positive margin should be followed closely.en_US
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technological Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCanceren_US
dc.subjecthydrochlorothiazideen_US
dc.subjectrecurrenceen_US
dc.subjectskinen_US
dc.subjectBasal-Cell Carcinomaen_US
dc.subjectRisk-Factorsen_US
dc.subjectMetastasisen_US
dc.subjectPopulationen_US
dc.titleThe Effect of Hydrochlorothiazide on the Recurrence of Nonmelanoma Skin Cancer: a 7-Year Retrospective Study Comprising 300 Patientsen_US
dc.typeArticleen_US
dc.departmentTOBB ETÜen_US
dc.identifier.volume53en_US
dc.identifier.issue3en_US
dc.identifier.startpage752en_US
dc.identifier.endpage760en_US
dc.identifier.wosWOS:001022334700015en_US
dc.identifier.scopus2-s2.0-85163624085en_US
dc.institutionauthor-
dc.identifier.pmid37476909en_US
dc.identifier.doi10.55730/1300-0144.5638-
dc.authorscopusid57194264417-
dc.authorscopusid57850708200-
dc.authorscopusid57218773138-
dc.authorscopusid57194474692-
dc.authorscopusid56786442900-
dc.authorscopusid57222441725-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.scopusqualityQ3-
dc.identifier.trdizinid1191047en_US
item.openairetypeArticle-
item.languageiso639-1en-
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
crisitem.author.dept03.14. Department of Internal Medicine-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
TR Dizin İndeksli Yayınlar / TR Dizin Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
Show simple item record



CORE Recommender

Page view(s)

58
checked on Dec 16, 2024

Google ScholarTM

Check




Altmetric


Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.