Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/10487
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dc.contributor.authorAliyev, Dostali-
dc.contributor.authorAkkemik, Umit-
dc.contributor.authorAşık, İbrahim-
dc.date.accessioned2023-07-14T20:18:03Z-
dc.date.available2023-07-14T20:18:03Z-
dc.date.issued2023-
dc.identifier.issn1078-6791-
dc.identifier.urihttps://hdl.handle.net/20.500.11851/10487-
dc.description.abstractContext . Osteoarthritis (OA) is the most common form of arthritis, affecting an estimated 302-million people worldwide, and it's a leading cause of disability among older adults. Current treatments for OA are largely unsatisfactory. Ozone is an inexpensive, accessible, and easily applicable treatment for OA. Objective . The study aimed to retrospectively evaluate the effects of a short-term, three-month OA treatment using an intra-articular ozone injection, on pain and physical function in patients with stage 2-3 knee OA. Design . The research team designed the study as a retrospective review of files from a hospital's archive as well as the results of a follow-up questionnaire about pain that patients completed at a related clinic. Setting . The study took place at the Algology Clinic at Ankara University in Ankara, Turkey. Participants . Participants were 94 patients, aged between 28 and 75 years, with stage 2-3 OA who had applied to the clinic between January 1, 2018 and January 1, 2020 and had received an intra-articular ozone injection. Intervention . Participants received intra-articular ozone treatments at a dose of 10 ml at 15 mcg/ml for 4 weeks, once a week. Outcome Measures . Participants completed a visual analogue score (VAS) and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), measuring pain at baseline and at one month and at 3 months postintervention. The study also determined if the treatment had an effect on analgesic drug use and measured patient satisfaction. Results . The decreases in participants' pain scores on both scales were statistically significant at one month and at 3 months postintervention (P =.000). The need for analgesic medication had decreased for 56 participants (61.5%) at one month postintervention and for 50 (54.9%) at 3 months postintervention. Of the 94 participants, 66 (70.2%) were satisfied and 28 (29.8) weren't. Conclusions . The intra-articular injection of ozone, applied once a week for 4 weeks, resulted in a reduction in pain in stage 2-3 knee OA, without any side effects. However, further studies are needed to resolve the uncertainties in dosage, number of sessions, and intervals for intra-articular ozone injections. The current study's results need support from further prospective studies that can evaluate the efficacy of ozone treatment for a longer period of time.en_US
dc.language.isoenen_US
dc.publisherInnovision Professional Mediaen_US
dc.relation.ispartofAlternative Therapies In Health and Medicineen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectTherapyen_US
dc.subjectHipen_US
dc.subjectRecommendationsen_US
dc.subjectPathogenesisen_US
dc.subjectDisabilityen_US
dc.subjectManagementen_US
dc.subjectEtiologyen_US
dc.subjectObesityen_US
dc.subjectImpacten_US
dc.titleEfficacy of an Intra-Articular Ozone Injection for Chronic Knee Pain Due To Osteoarthritisen_US
dc.typeArticleen_US
dc.departmentTOBB ETÜen_US
dc.identifier.volume29en_US
dc.identifier.issue1en_US
dc.identifier.startpage24en_US
dc.identifier.endpage28en_US
dc.authoridAKKEMIK, UMIT/0000-0001-8483-5416-
dc.identifier.wosWOS:000963220700003en_US
dc.identifier.scopus2-s2.0-85144595818en_US
dc.institutionauthor-
dc.identifier.pmid36239567en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.scopusqualityQ3-
item.openairetypeArticle-
item.languageiso639-1en-
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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